7 November 2019: New INNODERM publication in Nature Communication

The newest INNODERM publication has been published in Nature Communications by consortium partner TUM. In the publication, the authors present a homogentisic acid-derived pigment (HDP) for biocompatible intracellular labeling of macrophages with strong optoacoustic contrast efficient enough to resolve single cells with RSOM against a strong blood background. This work expands the sparse palette of macrophage labels for in vivo optoacoustic imaging and facilitate research on macrophage functionality and behavior.

Weidenfeld, I., Zakian, C., Duewell, P., Chmyrov, A., Klemm, U., Aguirre, J., Ntziachristos, V., & Stiel, A. Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages. Nat Commun 10, 5056 (2019). https://doi.org/10.1038/s41467-019-13041-4