Scientific and Technical Publications

Peer-reviewed publications

Englert, L., Riobo, L., Schönmann, C., Ntziachristos, V., and Aguirre, J. (2022) Enabling the autofocus approach for parameter optimization in planar measurement geometry clinical optoacoustic imaging, Journal of Biophotonics,

He, H., Schönmann, C., Schwarz, M., Hindelang, B., Bereznhoi, A., Steimle-Grauer, A., Darsow, U., Aguirre, J., and Ntziachristos, V. (2022) Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo, Nature Communications 13, 2803,

Hindelang, B., Nau, T., Englert, L., Berezhnoi, A., Lauffer, F., Darsow, U., Biedermann, T., Eyerich, K., Aguirre, J., and Ntziachristos, V. (2022) Enabling precision monitoring of psoriasis treatment by optoacoustic mesoscopy, Science Translational Medicine, 14, 644,

Hindelang, B., Aguirre, J., Berezhnoi, A., Biedermann, T., Darsow, U., Eberlein, B., & Ntziachristos, V. (2021), Quantification of skin sensitivity to ultraviolet radiation using ultrawideband optoacoustic mesoscopy. British Journal of Dermatology, 184: 352-354. 

Nat. Biomed. Eng. cover featuring an artist’s interpretation of optoacoustic imaging for tumor detection and treatment (Haedicke et al., 2020)

Facheris P, De Santis M, Gargiulo L, Pavia G, Valenti M, Manara S, Borroni RG, Costanzo A, Narcisi A. Concomitant Pyoderma Gangrenosum-like and Amicrobial Pustulosis of the Folds: a Case Report. J Clin Immunol. 2020 Oct;40(7):1038-1040. doi: 10.1007/s10875-020-00819-1. Epub 2020 Jul 9. PMID: 32648026; PMCID: PMC7505873.

Razansky D, and Ntziachristos V. Optical and Optoacoustic Imaging. Recent Results Cancer Res. 2020;216:155-187. doi: 10.1007/978-3-030-42618-7_5. PMID: 32594387.

Hindelang, B., Aguirre, J., Berezhnoi, A., He, H., Eyerich, K., Ntziachristos, V., Biedermann, T., & Darsow, U. Optoacoustic mesoscopy shows potential to increase accuracy of allergy patch testing. Contact Dermatitis. 2020; 83: 206– 214.

Hindelang, B., Schönmann, C., Aguirre, J., Ntzchiachristos, V., Biedermann, T., & Darsow, U.  “Optoakustische Bildgebung – Licht rein, Schall raus?” Aktuelle Dermatologie 46 (2020): 171-178. DOI:10.1055/a-1072-7195

Haedicke K, Agemy L, Omar M, Berezhnoi A, Roberts S, Longo-Machado C, Skubal M, Nagar K, Hsu HT, Kim K, Reiner T, Coleman J, Ntziachristos V, Scherz A, & Grimm J. High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies. Nat Biomed Eng. 2020 Mar;4(3):286-297. doi: 10.1038/s41551-020-0527-8. Epub 2020 Mar 12. PMID: 32165736; PMCID: PMC7153756.

Weidenfeld, I., Zakian, C., Duewell, P., Chmyrov, A., Klemm, U., Aguirre, J., Ntziachristos, V., & Stiel, A. Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages. Nat Commun 10, 5056 (2019).

Berezhnoi, A., Aguirre, J., Hindelang, B., Garzorz-Stark, N., Omar, M., Darsow, U., Eyerich, K. & Ntziachristos, V. “Optical features of human skin revealed by optoacoustic mesoscopy in the visible and short-wave infrared regions,” Opt. Lett. 44, 4119-4122 (2019). 

Moustakidis, S., Omar, M., Aguirre, J., Mohajerani, P. and Ntziachristos, V. (2019), Fully automated identification of skin morphology in raster-scan optoacoustic mesoscopy using artificial intelligence. Med. Phys., 46: 4046-4056.

J. Biophotonics Nov. 2018 cover featuring an RSOM image (Berezhnoi et al., 2018).

Nitkunanantharajah, S. Zahnd, G. Olivo, M. Navab, N. Mohajerani P., & Ntziachristos, V., “Skin Surface Detection in 3D Optoacoustic Mesoscopy Based on Dynamic Programming,” in IEEE Transactions on Medical Imaging, vol. 39, no. 2, pp. 458-467, Feb. 2020, doi: 10.1109/TMI.2019.2928393.

Hadjipanayi E, Moog P, Bekeran S, Kirchhoff K, Berezhnoi A, Aguirre J, Bauer AT, Kükrek H, Schmauss D, Hopfner U, Isenburg S, Ntziachristos V, Ninkovic M, Machens HG, Schilling AF, Dornseifer U. In Vitro Characterization of Hypoxia Preconditioned Serum (HPS)-Fibrin Hydrogels: Basis for an Injectable Biomimetic Tissue Regeneration Therapy. J Funct Biomater. 2019 May 13;10(2):22. doi: 10.3390/jfb10020022. PMID: 31086048; PMCID: PMC6616457.

Omar, M., Aguirre, J. & Ntziachristos, V. Optoacoustic mesoscopy for biomedicine. Nat Biomed Eng 3, 354–370 (2019).

Aguirre, J., Berezhnoi, A., He, H., Schwarz, M., Hindelang, B., Omar, M., & Ntziachristos, V. “Motion Quantification and Automated Correction in Clinical RSOM,” in IEEE Transactions on Medical Imaging, vol. 38, no. 6, pp. 1340-1346, June 2019, doi: 10.1109/TMI.2018.2883154.

Hindelang, B., Aguirre, J., Schwarz, M., Berezhnoi, A., Eyerich, K., Ntziachristos, V., Biedermann, T. & Darsow, U. (2019), Non-invasive imaging in dermatology and the unique potential of raster-scan optoacoustic mesoscopy. J Eur Acad Dermatol Venereol, 33: 1051-1061.

Stylogiannis, A., Prade, L., Buehler, A., Aguirre, J., Sergiadis, G. & Ntziachristos, V. Continuous wave laser diodes enable fast optoacoustic imaging, Photoacoustics, v. 9, 31-38, 2018, ISSN 2213-5979,

Aguirre, J., Hindelang, B., Berezhnoi, A., Darsow, A., Lauffer, F., Eyerich, K., Biedermann, T., & Ntziachristos, V., Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy, Photoacoustics, Volume 10, 2018, Pages 31-37, ISSN 2213-5979,

Berezhnoi, A, Schwarz, M, Buehler, A, Ovsepian, SV, Aguirre, J, & Ntziachristos, V. Assessing hyperthermia-induced vasodilation in human skin in vivo using optoacoustic mesoscopy. J. Biophotonics. 2018; 11:e201700359.

Nat. Biomed. Eng. cover featuring an RSOM image of healthy skin (Aguirre et al., 2017).

Schwarz, M., Garzorz-Stark, N., Eyerich, K., Aguirre, J., & Ntziachristos, V. Motion correction in optoacoustic mesoscopy. Sci Rep 7, 10386 (2017).

Narcisi, A., Favaro, R. & Costanzo, A. Diagnostic imaging: Listening in to skin disease. Nat Biomed Eng 1, 0076 (2017).

Aguirre, J., Schwarz, M., Garzorz, N., Omar, M., Buehler, A., Eyerich, K. & Ntziachristos, V. Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy. Nat Biomed Eng 1, 0068 (2017).

Schwarz, M., Soliman, D., Omar, M., Buehler, A., Ovsepian, S. V., Aguirre, J., & Ntziachristos, V. (2017). Optoacoustic Dermoscopy of the Human Skin: Tuning Excitation Energy for Optimal Detection Bandwidth with Fast and Deep Imaging in vivo. IEEE Transactions on Medical Imaging36(6), 1287–1296.

Talamonti M, Galluzzo M, van den Reek JM, de Jong EM, Lambert JLW, Malagoli P, Bianchi L, & Costanzo A. Role of the HLA-C*06 allele in clinical response to ustekinumab: evidence from real life in a large cohort of European patients. Br J Dermatol. 2017 Aug;177(2):489-496. doi: 10.1111/bjd.15387. Epub 2017 Jun 22. PMID: 28207934.