Scientific and Technical Publications

Peer-reviewed publications

He, H., Fischer, C., Darsow, U. et al. (2024) Quality control in clinical raster-scan optoacoustic mesoscopy, 35, 100582, Photoacoustics, https://www.sciencedirect.com/science/article/pii/S2213597923001350 

He, H., Fasoula, N.-A., Karlas, A., Omar, M., Aguirre, J., Lutz, J., Kallmayer, M., Füchtenbusch, M., Eckstein, H.-H., Ziegler, A., & Ntziachristos, V. (2023) Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy, Light: Science and Applications, https://www.nature.com/articles/s41377-023-01275-3s

Englert, L., Lacalle-Aurioles, M., Mohamed, N.-V., Lépine, P., Mathur, M., Ntziachristos, V., Durcan T.M. and Aguirre, J. (2023) Fast 3D Optoacoustic Mesoscopy of Neuromelanin Through Entire Human Midbrain Organoids at Single-Cell Resolution, Laser & Photonics Reviews, https://onlinelibrary.wiley.com/doi/10.1002/lpor.202300443

Nau, T., Schönmann, C., Hindelang, B., Riobo, L., Doll, A., Schneider, S., Englert, L., He, H., Biedermann, T., Darsow, U., Lauffer, F., Ntziachristos, V., & Aguirre, J. (2023) Raser-scanning optoacoustic mesoscopy biomarkers for atopic dermatitis skin lesions, Photoacoustics, https://doi.org/10.1016/j.pacs.2023.100513

Englert, L., Riobo, L., Schönmann, C., Ntziachristos, V., & Aguirre, J. (2022) Enabling the autofocus approach for parameter optimization in planar measurement geometry clinical optoacoustic imaging, Journal of Biophotonics, https://doi.org/10.1002/jbio.202200032

He, H., Schönmann, C., Schwarz, M., Hindelang, B., Bereznhoi, A., Steimle-Grauer, A., Darsow, U., Aguirre, J., and Ntziachristos, V. (2022) Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo, Nature Communications, 13, 2803, https://www.nature.com/articles/s41467-022-30471-9

Hindelang, B., Nau, T., Englert, L., Berezhnoi, A., Lauffer, F., Darsow, U., Biedermann, T., Eyerich, K., Aguirre, J., and Ntziachristos, V. (2022) Enabling precision monitoring of psoriasis treatment by optoacoustic mesoscopy, Science Translational Medicine, 14, 644, https://www.science.org/doi/10.1126/scitranslmed.abm8059

Hindelang, B., Aguirre, J., Berezhnoi, A., Biedermann, T., Darsow, U., Eberlein, B., & Ntziachristos, V. (2021) Quantification of skin sensitivity to ultraviolet radiation using ultrawideband optoacoustic mesoscopy, British Journal of Dermatology, 184: 352-354. https://doi.org/10.1111/bjd.19463 

Nat. Biomed. Eng. cover featuring an artist’s interpretation of optoacoustic imaging for tumor detection and treatment (Haedicke et al., 2020)

Facheris, P., De Santis, M., Gargiulo, L., Pavia, G., Valenti, M., Manara, S., Borroni, R.G., Costanzo, A., & Narcisi, A. (2020) Concomitant Pyoderma Gangrenosum-like and Amicrobial Pustulosis of the Folds: a Case Report. Journal of Clinical Immunology, 40(7):1038-1040. doi: 10.1007/s10875-020-00819-1. 

Razansky D, and Ntziachristos V. (2020) Optical and Optoacoustic Imaging. Recent Results Cancer Research, 216:155-187. doi: 10.1007/978-3-030-42618-7_5.

Hindelang, B., Aguirre, J., Berezhnoi, A., He, H., Eyerich, K., Ntziachristos, V., Biedermann, T., & Darsow, U. (2020) Optoacoustic mesoscopy shows potential to increase accuracy of allergy patch testing. Contact Dermatitis, 83: 206– 214, https://doi.org/10.1111/cod.13563

Hindelang, B., Schönmann, C., Aguirre, J., Ntzchiachristos, V., Biedermann, T., & Darsow, U.  (2020) Optoakustische Bildgebung – Licht rein, Schall raus?, Aktuelle Dermatologie, 46: 171-178, DOI:10.1055/a-1072-7195

Haedicke, K., Agemy, L., Omar, M., Berezhnoi, A., Roberts, S., Longo-Machado, C., Skubal, M., Nagar, K., Hsu, H.T., Kim, K., Reiner, T., Coleman, J., Ntziachristos, V., Scherz, A., & Grimm, J. (2020) High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies. Nature Biomedical Engineering, 4(3):286-297, doi: 10.1038/s41551-020-0527-8. 

Weidenfeld, I., Zakian, C., Duewell, P., Chmyrov, A., Klemm, U., Aguirre, J., Ntziachristos, V., & Stiel, A. (2019) Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages. Nature Communications, 10, 5056, https://doi.org/10.1038/s41467-019-13041-4

Berezhnoi, A., Aguirre, J., Hindelang, B., Garzorz-Stark, N., Omar, M., Darsow, U., Eyerich, K. & Ntziachristos, V. (2019) Optical features of human skin revealed by optoacoustic mesoscopy in the visible and short-wave infrared regions, Optical Letters, 44, 4119-4122, https://doi.org/10.1364/OL.44.004119 

Moustakidis, S., Omar, M., Aguirre, J., Mohajerani, P., & Ntziachristos, V. (2019) Fully automated identification of skin morphology in raster-scan optoacoustic mesoscopy using artificial intelligence, Medical Physics, 46: 4046-4056, https://doi.org/10.1002/mp.13725

J. Biophotonics Nov. 2018 cover featuring an RSOM image (Berezhnoi et al., 2018).

Nitkunanantharajah, S., Zahnd, G., Olivo, M., Navab, N., Mohajerani, P., & Ntziachristos, V. (2020) Skin Surface Detection in 3D Optoacoustic Mesoscopy Based on Dynamic Programming,” in IEEE Transactions on Medical Imaging, vol. 39, no. 2, pp. 458-467, doi: 10.1109/TMI.2019.2928393.

Hadjipanayi, E., Moog, P., Bekeran, S., Kirchhoff, K., Berezhnoi, A., Aguirre, J., Bauer, A.T., Kükrek, H., Schmauss, D., Hopfner, U., Isenburg, S., Ntziachristos, V., Ninkovic, M., Machens, H.G., Schilling, A.F., Dornseifer, U. (2019) In Vitro Characterization of Hypoxia Preconditioned Serum (HPS)-Fibrin Hydrogels: Basis for an Injectable Biomimetic Tissue Regeneration Therapy, Journal of Functional Biomaterials, 10(2):22. doi: 10.3390/jfb10020022. 

Omar, M., Aguirre, J. & Ntziachristos, V. (2019) Optoacoustic mesoscopy for biomedicine, Nature Biomedical Engineering 3, 354–370, https://doi.org/10.1038/s41551-019-0377-4

Aguirre, J., Berezhnoi, A., He, H., Schwarz, M., Hindelang, B., Omar, M., & Ntziachristos, V. (2019) Motion Quantification and Automated Correction in Clinical RSOM, IEEE Transactions on Medical Imaging, vol. 38, no. 6, pp. 1340-1346, doi: 10.1109/TMI.2018.2883154.

Hindelang, B., Aguirre, J., Schwarz, M., Berezhnoi, A., Eyerich, K., Ntziachristos, V., Biedermann, T. & Darsow, U. (2019) Non-invasive imaging in dermatology and the unique potential of raster-scan optoacoustic mesoscopy, Journal of the European Academy of Dermatology and Venerology, 33: 1051-1061, https://doi.org/10.1111/jdv.15342

Stylogiannis, A., Prade, L., Buehler, A., Aguirre, J., Sergiadis, G. & Ntziachristos, V. (2018) Continuous wave laser diodes enable fast optoacoustic imaging, Photoacoustics, v. 9, 31-38, ISSN 2213-5979, https://doi.org/10.1016/j.pacs.2017.12.002.

Aguirre, J., Hindelang, B., Berezhnoi, A., Darsow, A., Lauffer, F., Eyerich, K., Biedermann, T., & Ntziachristos, V. (2018) Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy, Photoacoustics, Volume 10, Pages 31-37, ISSN 2213-5979, https://doi.org/10.1016/j.pacs.2018.02.002.

Berezhnoi, A., Schwarz, M., Buehler, A., Ovsepian, S.V., Aguirre, J., & Ntziachristos, V. (2018) Assessing hyperthermia-induced vasodilation in human skin in vivo using optoacoustic mesoscopy. Journal of Biophotonics; 11:e201700359.  https://doi.org/10.1002/jbio.201700359

Nat. Biomed. Eng. cover featuring an RSOM image of healthy skin (Aguirre et al., 2017).

Schwarz, M., Garzorz-Stark, N., Eyerich, K., Aguirre, J., & Ntziachristos, V. (2017) Motion correction in optoacoustic mesoscopy. Science Reports, 7, 10386. https://doi.org/10.1038/s41598-017-11277-y

Narcisi, A., Favaro, R. & Costanzo, A. (2017) Diagnostic imaging: Listening in to skin disease. Nature Biomedical Engineering 1, 0076. https://doi.org/10.1038/s41551-017-0076

Aguirre, J., Schwarz, M., Garzorz, N., Omar, M., Buehler, A., Eyerich, K., & Ntziachristos, V. (2017) Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy. Nature Biomedical Engineering 1, 0068. https://doi.org/10.1038/s41551-017-0068

Schwarz, M., Soliman, D., Omar, M., Buehler, A., Ovsepian, S. V., Aguirre, J., & Ntziachristos, V. (2017). Optoacoustic Dermoscopy of the Human Skin: Tuning Excitation Energy for Optimal Detection Bandwidth with Fast and Deep Imaging in vivo. IEEE Transactions on Medical Imaging36(6), 1287–1296. https://doi.org/10.1109/TMI.2017.2664142

Talamonti, M., Galluzzo, M., van den Reek, J.M., de Jong, E.M., Lambert, J.L.W., Malagoli, P., Bianchi, L., & Costanzo, A. (2017) Role of the HLA-C*06 allele in clinical response to ustekinumab: evidence from real life in a large cohort of European patients. British Journal of Dermatology; 177(2):489-496. doi: 10.1111/bjd.15387.