Check out our newest publication from lead author Juan Aguirre at the Technical University of Munich. The paper, available in Nature Biomedical Engineering is titled ‘Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy.’
In this paper, the authors demonstrate that raster-scan optoacoustic mesoscopy (RSOM) implemented in ultra-broadband detection mode bridges the depth capabilities of ultrasound and the resolution range and high contrast of optical methods in clinical dermatology. They use RSOM then to visualize skin morphology and vascular patterns in the dermis and sub-dermis of psoriasis patients, enabling quantification of inflammation and other biomarkers of psoriasis without the need for contrast agents. Implemented in a handheld device, the authors show that label-free biomarkers detected by RSOM correlate with clinical score, giving weight that this method can be extended to assess a larger spectrum of dermatological conditions in the future.
Aguirre, J., Schwarz, M., Garzorz, N. et al. Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy. Nat Biomed Eng 1, 0068 (2017). https://doi.org/10.1038/s41551-017-0068